A natural way to help SAD

SAD Seasonal Affective Disorder

I’m looking out of the window and it’s a grey, cold, overcast day. Just the sort of day that encourages Seasonal Affective Disorder or SAD.

SAD is associated with a lack of energy and depression. In some 8% of people it’s serious enough to need treatment, but in some degree it affects at least a quarter of us. And almost all of us feel less upbeat after a spell of gloomy weather.

SAD – or the ‘winter blues’ – is caused by insufficient sunlight. The result is a general lethargy and, in some people, sleep problems, lower libido and an urge to overeat. There’s even a charity devoted to helping victims of SAD.

The connection with mood is because light passes through the eye to the hypothalamus, a part of the brain that controls the production of many of your hormones – including oxytocin, the ‘love’ hormone.

Lack of sunlight in winter months leads to insufficient vitamin D

Lack of sunlight is responsible for even more serious conditions than a general feeling of malaise.

If you are like the majority of people in our modern world, you work indoors almost all the time. Then you go home, cook and relax by reading or watching TV – so you continue to be indoors.

The result is that you don’t get enough sunlight and therefore you don’t get enough vitamin D. Yet we are evolved to absorb sunlight and when we do not get enough, our bodies don’t function well.

Vitamin D plays a major role in maintaining overall health. It regulates over 1,000 different genes – upregulating health-promoting genes and downregulating health-threatening genes.

Vitamin D and cancer

Research shows that sub-optimal levels of vitamin D3 in the blood are linked to high blood pressure, heart disease, osteoporosis, possibly multiple sclerosis and an increased risk of various forms of cancer, including breast, colon and prostate cancer.

Significantly, researchers have tracked mortality rates from breast cancer, prostate cancer, colon, and ovarian cancer and found them lower in the sunnier states of the USA.

Cells in your body have vitamin D “receptors”, and the presence of these specific receptors mean vitamin D is actually a hormone, rather than a vitamin.

 We know that vitamin D plays an important role in how cells develop. So it is perhaps not surprising that when vitamin D is directly applied to ‘D receptors’ in the laboratory, cancer cells stop growing and multiplying, according to research published by the National Cancer Institute in America.

Although all males who lack adequate levels of vitamin D are more vulnerable to prostate problems, males originally of African origin are especially at risk of prostate cancer.

Optimum vitamin D lowers risk of dementia and heart disease

Sub-optimal levels of vitamin D can be injurious to health generally and they are also linked to dementia. In fact, a 7 year study published in the US National Library of Medicine shows that low levels of vitamin D increase the risk of dementia almost 20 times!

Vitamin D deficiency is also very common in people with cardiovascular disease. A 2010 survey showed that almost all people with heart failure have reduced D levels. So much so that low vitamin D status is now acknowledged as an independent predictor for arterial diseases, including heart attacks and strokes.

There are dozens of studies that show you need vitamin D to maintain your cardiovascular health. But in the winter it’s virtually impossible to get the level you need from sunlight. And few foods can provide enough to make up the difference.

Take a vitamin D3 supplement

A supplement of vitamin D3 – the natural version that is created by sunlight – is the answer.

But it’s important to make sure you’re taking the proper dose. Studies of cardiovascular patients who take only an average of 500 IU a day generally show little benefit, whereas those taking 2,000 IU do.

Vitamin D and diabetes

People with diabetes have lower levels of vitamin D than the general population. A vitamin D deficiency makes you almost twice as likely to progress to insulin resistance, the pre-cursor of diabetes or ‘pre-diabetes’. And more than doubles your risk for progressing to type II diabetes (see references).

On the other hand, a study in the American Journal of Clinical Nutrition showed that a supplement level of vitamin D3 at 2,000 IU a day slows the progression from pre-diabetes to diabetes.

When overweight, non-diabetic adults supplemented with 2,000 IU/day of vitamin D or a placebo for 16 weeks, the vitamin D group had significantly improved insulin secretion and glucose clearance from their blood. The control subjects saw a worsening of these markers.

Ensuring that you have an optimum intake of vitamin D is essential to combat SAD and protect against cancer, heart disease, dementia and diabetes.

One a day vitamin pills with just the Recommended Daily Amount (RDA/RNI) are sub-optimal, as the RDA/RNI in the UK and EU is inadequate, particularly for winter.

You can get a free report by Dr Paul Clayton and Colin Rose on the case for optimum vitamin D and advice from this link. http://www.nutrishield.com/the-products/vitamin-d/


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Dr Paul Clayton designed NutriShield as a comprehensive healthbutton-2 supplement with OPTIMUM levels of essential nutrients. See more detail elsewhere on this site or click on the button.

Dr Paul Clayton’s best-selling book Health Defence is available from booksellers.

Read it here online or see the website www.healthdefence.com for excerpts and links to buy direct from the publisher.

See online here for delicious recipes from the Health Defence Cookbook incorporating healthy foods featuring in a Mediterranean Diet. Combined 3 courses strip


Serum vitamin D deficiency as a predictor of incident non-Alzheimer dementias: a 7-year longitudinal study. Annweiler C, Rolland Y, Schott AM, Blain H, Vellas B, Beauchet O. Dement Geriatr Cogn Disord. 2011;32(4):273-8.

Vitamin D deficiency and myocardial diseases. Pilz S, Tomaschitz A, Drechsler C, Dekker JM, Marz W Mol Nutr Food Res. 2010 Aug;54(8):1103-13

Vitamin D status and peripheral arterial disease: evidence so far. Chua GT, Chan YC, Cheng SW.. Vasc Health Risk Manag. 2011;7:671-5.

Recruitment and results of a pilot trial of vitamin D supplementation in the general population of Australia. Tran B, Armstrong BK, Carlin JB, et al. J Clin Endocrinol Metab. 2012 Dec;97(12):4473-80.

Lipoprotein lipase links vitamin D, insulin resistance, and type 2 diabetes: a cross-sectional epidemiological study. Huang Y, Li X, Wang M, et al. Cardiovasc Diabetol. 2013;12:17.

Effects of vitamin D and calcium supplementation on pancreatic beta cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial. Mitri J, Dawson-Hughes B, Hu FB, Pittas AG.. Am J Clin Nutr. 2011 Aug;94(2):486-94.

Grapeseed protects the brain

Medical News Today mostly tracks developments in conventional medicines, but a recent article highlighted multiple impressive therapeutic benefits of grapeseed extract as a supplement.


It’s difficult to get enough grapeseed extract proanthocyanidins from eating raw grapes or drinking grape juice or wine.


Grapeseed benefits include:

  • Preventing cognitive decline

    Because grapeseed extract is very high in the polyphenol group called proanthocyanidins, which are neuro-protective in the hippocampus, it may prevent cognitive loss with ageing.

    A paper in the Journal of Alzheimer’s Disease published by researchers at the Mount Sinai School of Medicine in New York City confirmed that grapeseed extract was able to prevent the formation of proteins in the brain called oligomers. These proteins are seen in Alzheimer’s patients.

    The researchers “strongly suggest that GSPE (grape seed proanthocyanidin extract) should be further tested as a potential prevention and/or therapy for AD [Alzheimer’s Disease]”.

  • Improving bone strength

    Grapeseed extract combined with calcium in the diet has a “beneficial effect on bone formation and bone strength“, according to research published in the Journal of Musculoskeletal & Neuronal Interactions.

  • Helping to prevent skin cancer

    Grapeseed proanthocyanidins can prevent the development of cancer. A study, published in the journal Molecular Nutrition & Food Research, found that grapeseed extracts “could be useful in the attenuation of the adverse UV-induced health effects in human skin.

  • Cutting the risk of high blood pressure

    According to one study, published in the journal Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, “grape seed proanthocyanidin extract (GSPE) provides superior antioxidant efficacy as compared to Vitamins C, E and β-carotene.”  Anti-oxidants help protect blood vessels from becoming damaged, which may prevent high blood pressure.

The Medical News Today article also cited research that indicates additional benefits as:

  • Anti-aging properties

    – protecting collagen and elastin in the skin

  • Protecting against pathogens

    – an immune enhancer

  • Treating diabetic retinopathy

  • Improving blood sugar control


NutriShield contains grapeseed extract and other polyphenols like green tea extract. However, a truly effective supplement should contain a range of nutrients that as far as possible reflects an ideal diet – Omega 3, carotenoids, CoQ10, betaine as well as vitamins E, K2, D3 and all the other essential vitamins and minerals at optimum levels.


If you enjoyed this article, please share it with family and friends (see buttons below).

CTA Register NewsletterAnd register now for a free e-newsletter on the latest in nutrition and health research.

You can follow us on www.facebook.com/nutrishield or www.twitter.com/colinrose40 for daily headline health tweets.

Dr Paul Clayton designed NutriShield as a comprehensive healthbutton-2 supplement with OPTIMUM levels of essential nutrients. See more detail elsewhere on this site or click on the button.

Health Defence bookDr Paul Clayton’s best-selling book Health Defence is available from most good bookstores. See the website www.healthdefence.com for excerpts and links to buy direct from the publisher.

See online here for delicious recipes from the Health Defence Cookbook  incorporating healthy foods featuring in a Mediterranean Diet. Combined 3 courses strip


“Grape Seed Polyphenolic Extract Specifically Decreases A[beta]*56 in the Brains of Tg2576 Mice.” Peng Liu, Lisa J. Kemper, Jun Wang, Kathleen R. Zahs, Karen H. Ashe, Giulio M. Pasinetti. Journal of Alzheimer’s Disease JAD 2011, Volume 26, Number 4,

“What are the benefits of Grapeseed Extract?” http://www.medicalnewstoday.com/articles/263332.php